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Duke University and Duke University Health System require all students, faculty and staff to receive the COVID-19 and influenza vaccines.  After you have officially accepted a position at Duke, you may request a religious or medical accommodation.


Work Arrangement: 
Requisition Number:  195218
Regular or Temporary:  Regular

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER
Date:  Jul 28, 2022

This Position is Grant Funded

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.



Shared Resource Laboratory Manager (RBL Immunology)


The Duke Human Vaccine Institute (DHVI), an international leader in the fight against infectious diseases, is seeking a highly motivated individual for the position of Shared Resource Laboratory Manager. Investigators at the DHVI conduct basic and translational research to develop novel vaccines, therapeutics and diagnostics for diseases such as COVID-19, HIV-1, tuberculosis, influenza, and Zika. 


The Duke Regional Biocontainment Laboratory (RBL) is a division of the DHVI and supports a wide portfolio of research programs. The RBL has three collaborative core units: Immunology, Virology, and Microbiology. The Immunology Unit is staffed by five technicians/analysts, and the Shared Resource Laboratory Manager will be responsible for managing all the Unit’s shared resource core research activities. She/he will also work at the bench to train staff, develop assays, and support funded research programs.



Job Responsibilities:

  • Ensure that all Unit work is performed under DHVI/RBL-approved Standard Operating Procedures (SOPs) and that all Unit staff are trained in and perform duties according to SOPs.
  • Provide day-to-day monitoring of safety issues for all activities in the Unit and ensure compliance with all safety regulations.
  • Develop, document, implement and manage Unit work practices, policies and procedures. Coordinate with research staff on issues which impact laboratory services.
  • Manage and supervise technical staff including recruitment, training, performance management, and professional skills development.
  • Work with shared resource customers to identify and order appropriate assays, prepare cost estimates, coordinate logistics, and review data.
  • In collaboration with the RBL Leadership, implement research plans and assist in formulating and implementing short- and long-range goals for the operation of the Immunology Unit; set priorities, assign responsibilities, and establish timetables/budgets/milestones. Project future needs and formulate strategies consistent with projections.
  • Liaise with investigators, RBL leadership and technical staff to solve specific operating problems and improve technical activities/assays/services/models.
  • Advise on and troubleshoot technical procedures, techniques and equipment, and maintain conformance with specific operational standards.
  • Prepare technical reports reflecting volume of work, procedures utilized and study results; coordinate the preparation of reports and analyses setting forth progress, adverse trends, and appropriate recommendations or conclusions.
  • Plan, run and analyze immunological assays (flow cytometry, multiplex bead array (Luminex platform), qRT-PCR, ELISA etc.).
  • Develop and document new immunological assays.
  • Perform additional duties as requested by RBL/DHVI leadership.



Work requires a bachelor’s degree in biology, immunology, biochemistry, molecular biology or a related field. Must be able to manage multiple and rapidly changing priorities and have ability to quickly learn new skills. Must be able to work in a team environment, be well-organized and have strong computer and communication skills.

Applicants must be willing to:

    • Work with hazardous biological agents handled at BSL2 and BSL3
    • Comply with vaccination requirements when necessary
    • Complete US Department of Justice screening for Select Agent registration
    • Complete Select Agent registration at Tier 1
    • Achieve external certification for independent work at BSL3


Preferred Skills:

  • Exceptional interpersonal skills – especially teamwork and customer engagement
  • Strong understanding of, and ability to explain, basic laboratory math and scientific concepts (e.g. dilutions, molarity, unit conversion, standard curves etc.)
  • Proficiency with immunological assays such as Luminex-based cytokine assays, flow cytometry, qRT-PCR, and/or ELISA.


Minimum Qualifications




Bachelor of Science in Biology, Chemistry or Animal Science.




5 to 7 years of related Lab Research Analysis. Ability to communicate OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE equipment. clearly in oral and written form. Ability to work with information systems, automated and technical


Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh