RESEARCH TECHNICIAN II

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

POSITION DESCRIPTION AND REQUIREMENTS:

Research Technician II needed in the laboratory of Scott Floyd in the Departments of Radiation Oncology/Pharmacology Cancer Biology at Duke University School of Medicine. This position will focus on testing genetic and drug strategies to inhibit invasive growth of glioma cells in unique ex vivo models of brain cancer as well as studying immune therapy effects in combination with radiation therapy in mouse models of brain metastasis.

Primary duties and responsibilities:

-Perform experiments using ex vivo organotypic murine brain slice tumor model.

-Monitor tumor cell growth via bioluminescence imaging.

-Monitor tumor cell growth and invasion via stereoscope and confocal microscopy

-Care for laboratory mice.

-Perform basic laboratory mouse experiments with tumor induction, treatment and measurement.

-Perform experiments using CRISPR, molecular cloning, cell biology and biochemistry.

-Document results by maintaining logs, charting data, and preparing reports.

-Maintain an organized and complete electronic laboratory notebook detailing all experiments and associated actions.

-Keep project leader/PI informed by clearly communicating all important positive and negative results.

-Participate in journal clubs and assemble presentations to share project progress with laboratory members.

-Collaborate with lab members to advance common goals, projects, and maintenance activities.

-Perform routine laboratory inventory, ordering and stocking tasks.

-Participate in mentorship by working with and guiding undergraduate researchers.

-Work with lab manager and PI to keep equipment operating by following operating instructions, troubleshooting breakdowns, maintaining supplies, performing preventive maintenance, and calling for repairs.

-Maintain a safe and healthy work environment by complying with regulations and following standards and procedures.

-Protect organization's value by keeping research information confidential; and maintaining highest integrity in data collection and maintenance.

-Update job knowledge by participating in educational opportunities and reading technical bulletins.

Education:

B.S./B.A in biological sciences

Experience:

-Preferred: Minimum 1 year biological laboratory experience; proficiency in cell culture, genetics, molecular cloning, cellular biology, and biochemistry.

Qualifications:

-Exceptional organizational skills; meticulous attention to detail; committed to producing accurate and high-quality work.

-Self-motivated; committed to exceeding quality standards and providing exceptional services.

-Practiced documentation skills.

-Proficient at using multiple resources, quantitative, and qualitative research methodologies to capture and interpret information.

-Aware of basic safety procedures and willing to follow them to maintain a safe work environment.

-Willing and able to collaborate and expand job-related knowledge in a cooperative environment.

Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends onthe robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.