Work Arrangement: 
Requisition Number:  244568
Regular or Temporary:  Regular

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER
Date:  May 21, 2024

This Position is Grant Funded

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.


Division of Structural Biology – Duke Human Vaccine Institute


We are seeking a motivated and hardworking Research Technician II to support operations in the Division of Structural Biology. The primary overall responsibility of the position will be to assist in the operations of the lab, and to support protein expression, purification and crystallization for structural studies. 




  • Monitor inventory and ensure necessary supplies of stock are available for continuity of scientific work; maintain equipment as required. 
  • Perform laboratory duties and maintain documentation for general lab operations - MSDS's, chemical inventories, waste disposal, autoclaving, etc. as required. 
  • Assist in expression of proteins in commonly used systems (E coli, insect, mammalian). 
  • Assist in purification of proteins for structural studies. 
  • Assist in crystallization experiments. 
  • Maintain laboratory notebook and other documentation in an orderly and accurate fashion for tracking work progress, experiments, and results. 
  • Provide a summary of written work updates and plans each week. 
  • Perform other duties as assigned by the Principal Investigator and laboratory leadership. 


Required Qualifications at this Level

  • Education/Training: Work generally requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.
  • Experience: None required above education/training requirement. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE.



  • Demonstrated ability to work within a team, and to troubleshoot and resolve problems.
  • Experience in protein expression, purification and biochemistry desired. 


Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh