RESEARCH SCIENTIST

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Position Summary:

The Staff Research Scientist will play a key role in supporting the translational research mission of the Department of Neurosurgery and the Preston Robert Tisch Brain Tumor Center (PRTBTC). This position will contribute critical scientific leadership to ongoing research efforts, with a focus on glioma modeling, therapeutic target discovery, and preclinical and clinical investigations while supporting grant development, team management, and collaborative initiatives across departments.

Key Responsibilities:

· Lead and manage research projects aligned with the strategic objectives of the Ashley Lab and the PRTBTC, with a particular focus on genetically engineered mouse models of glioma, translational target discovery, and immune modulation.

· Contribute and participate in experimental design and execution.

· Develop and prepare grant applications to secure external funding from federal and private sources; collaborate on multi-investigator proposals.

· Supervise and train laboratory personnel, including junior scientists, graduate students, and technical staff, to ensure high-quality and reproducible research practices.

· Oversee experimental design, data generation, and analysis related to key lab initiatives, ensuring alignment with funded project goals.

· Prepare scientific manuscripts and contribute to data presentation for conferences, publications, and grant progress reports.

· Collaborate with internal and external investigators to advance shared research goals and promote interdisciplinary integration across research units.

· Maintain project timelines and ensure compliance with institutional, funding agency, and ethical guidelines.

· Provide regular updates to the Director of the Brain Tumor Center regarding project progress, research priorities, and strategic planning initiatives.

Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends onthe robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.