Postdoctoral Associate

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

This position will support several of our ongoing projects related to our studies examining the role of the tumor-intrinsic NLRP3 inflammasome pathway in immunotherapy resistance.  This will require experience in tissue culture work, flow cytometry, animal handling and experimentation, qrt-PCR, Western blot, as well as the execution and analysis of RNAseq/scRNAseq.  The individual in this position will be expected to keep accurate lab notes, perform experimental troubleshooting, discuss ongoing work and research trajectory both in group lab meetings and in one-on-one meetings with the PI, while also keeping abreast of the literature in the areas related to each project.  This individual will work under a senior research scientist and will be working in collaboration with another post-doctoral associate, a post-bac research assistant, and two laboratory technicians. 

Minimum Qualifications

Education

PhD Degree with a background in tumor immunology

Experience

• Interest and experience in working with murine tumor models required

• Significant experience in multi-parameter flow cytometry and in the design of cell-based assays required
   

Skills

• Excellent verbal and written communication skills in English with good organizational and analytical abilities

• Capable of working independently on assigned projects while thriving in a team-oriented environment

Preferences

• Experience in performing and analyzing bulk RNAseq/scRNAseq preferred

• Interest and experience in conducting spatial transcriptomic studies preferred

• Experience in conducting proximity ligation assays and fluorescence in situ hybridization on tumor tissue specimens preferred

• Previous grant writing experience preferred

Job Code: 00003820 POSTDOCTORAL ASSOCIATE
Job Level: 00

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