Work Arrangement: 
Requisition Number:  180048
Regular or Temporary:  Regular

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER
Date:  Dec 6, 2023

This Position is Fully Grant Funded


School of Medicine:


Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.


Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.



Duke Human Vaccine Institute

Alam Lab


The Duke Human Vaccine Institute (DHVI) performs basic and translational research to fight against major infectious diseases. DHVI is seeking Postdoctoral Associates to join our team in developing vaccines for HIV and beta-coronaviruses such as SARS-CoV-2.  The Duke Human Vaccine Institute is an interdisciplinary, interdepartmental institute dedicated to the study of host-pathogen interactions that can be translated into biologics and vaccines. DHVI is composed of a team of highly interactive investigators that have expertise in mucosal and systemic immunology, virology, molecular and structural biology, computational biology, and animal medicine. With these expertises, the DHVI is working collaboratoratively to develop vaccines and countermeasures against pathogens like HIV, SARS-CoV-2, and influenza.

We are seeking a highly motivated recent PhD graduate to join our team to work on the development and characterization of immunogens targeting a key broadly neutralizing epitope on HIV-1 Envelope. The work will involve studies on the immunogenicity of structure-based immunogen designs in novel knock-in mouse models, subsequently leading to studies in non-human primates. The goal of the project is to develop immunogens to be tested in human clinical trials for the induction of neutralizing antibody responses against a key HIV-1 vaccine target. The position will allow the Fellow to interact with and be mentored by leading investigators in the field and acquire advanced training and skills to pursue a future career in immunological research.    

Applicants should possess a PhD in Immunology or related biological sciences. In addition, the applicant should have an excellent working knowledge in cellular immunological and molecular biology techniques including flow cytometry, fluorescence/confocal microscopy, PCR and vector cloning for receptor expression. Experience in cell culture and FCM phenotyping, PAGE and WB analysis, chromatography techniques and ELISA assays is preferred. Familiarity with antibody-antigen binding interaction analyses using SPR, or BLI platforms would be a plus. The applicant should have a record of accomplishment that has either been published or is in press in highly regarded, peer-reviewed international journals. Ideal candidate will have the ability to work effectively with interdisciplinary teams and have an excellent oral and written communication skills.




Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh