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POSTDOCTORAL ASSOCIATE

Work Arrangement: 
Requisition Number:  179228
Regular or Temporary:  Regular
Location: 

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER
Date:  Jul 19, 2022

School of Medicine:

 

Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

 

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

 

 

Postdoctorial Associate  (Reitman Lab)

 

The goal of the Reitman Lab (https://radonc.duke.edu/research/reitman-lab ) is to make discoveries that guide the design of improved treatment strategies for children and adults with brain tumors. We leverage molecular biology techniques, genetically engineered mouse models and cancer genomic approaches to carry out our work. The Reitman Lab is based in the Department of Radiation Oncology and the team works closely with the faculty and staff in the Preston Robert Tisch Brain Tumor Center at Duke, the Department of Neurosurgery and the Duke Cancer Institute. We are interested in several research themes, including:

(1) using primary genetically engineered mouse models of pediatric and adult brain tumors to study mechanisms of tumorigenesis, mechanisms of treatment resistance, and candidate therapeutic strategies

(2) identifying new therapeutic dependencies associated with frequent cancer mutations

(3) identifying methods to increase the efficacy and decrease toxicity of radiation therapy for brain tumor patients

(4) using single cell genomic techniques to understand tumor heterogeneity, to define brain tumor lineage of origin, and to improve diagnosis and treatment for brain tumor patients

 

The job duties include the following:

· Organize overall research plan, and design individual experiments.

· Develop and utilize novel and existing mouse models of brain tumors.

· Design and perform experiments involving ionizing radiation treatments to mice and cell lines.

· Design and perform experiments in genetically engineered mouse models of brain tumors, gene editing, molecular cloning, cell biology and biochemistry.

· Care for laboratory mice.

· Develop and utilize technology for analyzing signal transduction in vitro and vivo.

· Prepare manuscripts for scientific publication with PI supervision.

· Maintain an organized and complete electronic laboratory notebook detailing all experiments in paper and electronic formats.

· Keep PI informed by pointing out all important positive and negative results.

· Keep equipment operating by following operating instructions; troubleshooting breakdowns; maintaining supplies; performing preventive maintenance; calling for repairs.

· Maintain safe and healthy work environment by complying with regulations and following standards and procedures.

· Protect organization's value by keeping research information confidential.

· Update job knowledge by participating in educational opportunities, networking and presenting at local, national and international meetings, and reading current primary literature.

· Provide a friendly working environment and be available to help teach research technicians and other trainees laboratory techniques and scientific methodology.

 

Min Degree Requirements:

·         Ph.D. or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.).

·         Should be used for post-doctoral fellows if the candidate has completed all of the requirements for a degree, but the degree has not been formally conferred; the candidate may present evidence of completion of the degree requirements, together with a statement documenting the date on which the degree is to be conferred.

 

Other Credential/Experiential Requirements:

The incumbent must be a true post-doctoral fellow registered with the Post Doc Office and per the following requirements:

·         The term of this appointment is limited (5 years with a possible extension for an additional year)

·         The appointment involves substantially full-time research or scholarship, which may include teaching responsibilities.

·         The appointment is viewed as preparatory for a full time academic or research career.

·         The appointment is not part of a clinical research training program, unless research training under the supervision of a senior mentor is a primary purpose of the appointment.

·         The appointee works under the supervision of a scholar or a department at Duke University.

·         The appointee has the freedom, and is expected to publish the results of his or her research or scholarship during the period of the appointment.

 

Minimum Qualifications

 

Education

See job description for education requirements.

 

Experience

 

See job description for requirements.

 

jd updated 2/24/2022

 

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

 

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

 

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

 


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