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Requisition Number::  167471
Date:  May 12, 2022

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER

School of Medicine:


Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.


Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.




Completed applications will be reviewed on an ongoing basis until position is filled.


Computational Approaches to Cancer Evolution

The Department of Population Health Sciences aspires to create a community built on collaboration, innovation, creativity, equity, and inclusivity of others without biases or prejudice of any kind. Our collective success depends on a robust exchange of ideas - an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, we are committed to diversity in the staff and faculty we hire, the policies we create, and the decisions we make.

The Ryser Laboratory at Duke University (Durham, NC, USA) is looking for a highly motivated Postdoctoral Associate in the field of computational biology and cancer evolution. The position will be funded by Marc D. Ryser, PhD who holds a joint appointment between the Departments Population Health Sciences and Mathematics. The appointment is for 2 year, and may be renewed for 1 year.


Overview. The successful applicant will use tools from mathematics, statistics, and bioinformatics to analyze and model genetic, epigenetic and imaging data from human breast and colorectal cancers. The overarching goal of the work is to elucidate the evolutionary dynamics of early carcinogenesis, and to develop evolutionary biomarkers that delineate aggressive from indolent early-stage lesions. The work will be performed in a cross-disciplinary setting, in collaboration with cancer biologists, surgeons and radiologists.


Qualifications. The successful applicant has a doctorate in computational biology, (bio)statistics, bioinformatics, applied mathematics or a related discipline. The position requires proficiency in the processing of sequencing data, statistical analysis of complex data sets, and analytic and/or simulation-based modeling of stochastic processes. The successful applicant demonstrates great attention to detail, works independently, takes initiative, has excellent written and verbal communication skills, and performs well in an interdisciplinary environment at the interface between the quantitative sciences and medicine. The successful candidate is expected to have a track record of first-author publication in peer-reviewed journals.



Please incude the requested additonal information above via PDF or web links with your application. 

Application. Interested applicants should submit the following documents:

  • Cover letter
  • Research statement (2 pages or less)
  • Curriculum vitae (4 pages or less)
  • Copies of 2 relevant first-author publications
  • A list containing the contact information for 3 references




Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh