POSTDOCTORAL ASSOCIATE

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Department of Dermatology within Duke’s School of Medicine has an opening for a Postdoctoral Associate. The position is located on – site at 3 Genome Court, Durham, N.C.

Min Degree Requirements: Ph.D. or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.). Should be used for post-doctoral fellows if the candidate has completed all of the requirements for a degree, but the degree has not been formally conferred; the candidate may present evidence of completion of the degree requirements, together with a statement documenting the date on which the degree is to be conferred.

Be Bold

The incumbent will perform the following tasks:

• Design, implement, and maintain scalable computational pipelines for multi-omics data, including bulk/single-cell RNA-seq, spatial transcriptomics, metagenomics, metabolomics, and potentially other omics layers using high-performance computing environments.

• Perform raw data processing, quality control, multi-modal data integration, and downstream analyses across diverse datasets (e.g., host transcriptome, microbial gene catalogs, spatial maps). • Lead host–microbiome interaction studies by integrating immune, epithelial, spatial, and microbial profiles to uncover key regulators of inflammation and tissue remodeling in gut and skin diseases.

• Apply and refine AI/ML methods, including deep learning, neural networks, and interpretable models (e.g., SHAP, BioMapAI) to discover multi-modal biomarkers, immune-microbe interaction modules, and spatially localized signatures associated with disease outcomes.

• Develop novel AI-driven frameworks to predict clinical phenotypes or treatment response based on high-dimensional omics data, incorporating temporal, spatial, and patient-specific features.

• Oversee data management, version-controlled codebases, and pipeline documentation to ensure reproducibility, cross-team collaboration, and scalable deployment.

• Collaborate with wet-lab scientists to guide experimental design, validate computational predictions with functional assays, and generate hypotheses for new biological discovery.

Choose Duke.

Join our award-winning team and be part of an inclusive culture that values excellence, innovation, and discovery. Duke University is consistently ranked among the top universities worldwide and is renowned for its cutting-edge research across disciplines. Beyond the engaging work, you'll also benefit from Duke's competitive benefits package, including health

insurance plans, generous paid time off, retirement programs with employer contributions, tuition assistance for employees and their children, and more.

Anticipated Pay Range:

Duke University provides an annual base salary range for this position as USD $62,000/year.. Duke University considers factors such as (but not limited to) scope and responsibilities of the position; candidate 's work experience, education/training, and key skills; internal peer equity; as well as market and organizational considerations when extending an offer.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.