POSTDOCTORAL ASSOCIATE

Work Arrangement: 
Requisition Number:  244661
Regular or Temporary:  Regular
Location: 

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER
Date:  Apr 24, 2024

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Occ Summary

General overview of position in the Batich Lab: Our Brain Tumor Center has a strong track record for successfully transitioning hired candidates to independent grant funding and next-level training or faculty positions. Duke University is in the vibrant research environment of the Research Triangle Park in Durham, North Carolina. Experience with preclinical mouse modelling, immunology, in vivo microscopy and bioluminescent imaging, immune cellular and molecular engineering, bioinformatics (single cell and other novel omics technologies), complex tissue culture and genome editing, and clinical trial development is desirable but is not required. We can provide necessary and systematic training in these areas depending on the prior experience, level of training and long-term goals.    

Our preclinical and clinical projects are spearheaded by an outstanding complement of graduate students, medical students, research associates, postdoctoral fellows, and junior and senior scientists within the Duke Brain Tumor Center.

Immunotherapeutic approaches include dendritic cell vaccines, peptide vaccines, protein vaccines, biologics such as antibodies, bispecific antibodies, oncolytic viruses, recombinant chemokines/cytokines T cell based and other cellular therapies. These immunotherapeutic strategies are to be evaluated in immunocompetent and immunocompromised preclinical models.

Preference will be given to highly self-motivated individuals interested in career advancement and growth opportunities. Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Postdoctoral candidate- A postdoctoral position is available in the Batich Lab in the Preston Robert Tisch Brain Tumor Center at Duke University. This position will involve basic and translational research based on engineered brain tumor models and studying the role of brain tumors in regulating endogenous dendritic cell immunity within the CNS. We are particularly interested in candidates who have prior research experience in the fields of Neuroscience, Neuro-oncology, and Biomedical Engineering. Duration of this training position would ideally be 3-5 years.

Please refer to our most recent publications:

https://aacrjournals.org/clincancerres/article/23/8/1898/123390/Long-term-Survival-in-Glioblastoma-with

https://www.nature.com/articles/nature14320

https://aacrjournals.org/clincancerres/article/26/20/5297/82883/Once-Twice-Three-Times-a-Finding-Reproducibility

https://link.springer.com/protocol/10.1007/978-1-0716-1884-4_33

 

Scope of work in the Batich Lab: Candidates should be enthusiastic about collaborative and interdisciplinary research, productive, and highly motivated to develop as independent scientists. Scope of the candidate’s project will be an extension of the current Batich Lab projects (spontaneous brain tumor development, endogenous dendritic cell migration in the CNS and brain tumors, immune cytokine and chemokine therapy with meningeal lymphatics, or CMV expression in high-grade gliomas). Candidate would meet regularly with Dr. Batich to propose upcoming experiments of the project, review data results that have been collected, analyzed, and interpreted by candidate, assemble data and results for scientific meeting presentations, abstracts, and grant submissions. Laboratory skills on immune assays and experience with preclinical models is preferred.  The candidate would generate their own data for manuscript preparation and assist Dr. Batich with manuscript and grant reviews on content related to the candidate’s project in Neuro-Oncology and Neuroimmunology. *Duration of this training position would ideally be 3-5 years.

 

 

Knowledge, Skills and Abilities

 

See job description for requirements.

 

Minimum Qualifications

 

 

Education

See job description for education requirements.

 

Experience

 

See job description for requirements.

 

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

 

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

 

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

 


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh