Work Arrangement: 
Requisition Number:  234255
Regular or Temporary:  Regular

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER
Date:  Jul 11, 2024
School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Drs. Deborah Muoio and Paul Grimsrud invite applications fora postdoc toral fellowship position at the Duke Molecular Physiology Institute(DMP I) within the School of Medicine at Duke University (Durham, NC). The DM PIand Duke University are part of a broad and dynamic community of acade mic andindustry scientists in the Research Triangle Park (RTP) area of N orth Carolina.The DMPI occupies a place of national and international le adership in the fightagainst major diseases and is a multi- and inter-di sciplinary Instituteencompassing basic and translational investigators a cross a variety ofscientific disciplines. Our mission is to produce inte grated multi-omics andphysiologic profiles of chronic human diseases, an d to use such profiles todevelop new disease detection strategies, novel therapies, and insights intodisease mechanisms. The Postdoctoral Associ ate will utilizemass-spectrometry-based proteomics and metabolomics to i nvestigate roles ofprotein post-translational modifications (PTMs) in re gulating mitochondrialphysiology and metabolic flux in heart, skeletal m uscle, and liver. The idealcandidate will have strong training in basic sciences and research interests inmolecular mechanisms of chronic metabo lic disorders or conditions such as obesity,diabetes, cardiovascular dis ease, and aging. Although candidates with expertisein all areas of basic science research will be considered, strong preferencewill be given to those with experience in analytical chemistry, massspectrometry, quantitative proteomics and/or computational biology. Thisposition offers a vib rant and highly interactive academic setting in a newstate-of-the-art re search facility, along with NIH-sponsored funding, access tooutstanding resources and technology platforms, strong computational supportfrom the DMPI Computational Biology Core, and a friendly, collaborative, andinte rdisciplinary group of colleagues in both the clinical and basic science s.

Min DegreeRequirements:  P h.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.). Should be used for post-doctoral fellows if the candidate has completedall the require ments for a degree, but the degree has not been formallyconferred; the c andidate may present evidence of completion of the degreerequirements, t ogether with a statement documenting the date on which thedegree is to b e conferred.

The candidate will have a minimum of a PhD, p referably inanalytical chemistry or biochemistry. Prior experience in pr oteomics is highlydesirable and formal training in bioinformatics/comput er science would bebeneficial.

Interestedcandidates should conta ct Paul Grimsrud at and/or DebMuoio at muoio@duke .edu.


Duke University is an Affirmative Action/Equal Oppo rtunityEmployer committed to providing employment opportunity without re gard to anindividual's age, color, disability, genetic information, gend er, genderexpression, gender identity, national origin, race, religion, sex, sexualorientation, or veteran status.

Minimum Qualifications


See job description for education requirements.


See job description for requirements.


Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh