LAB RESEARCH ANALYST I

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Position Description:

Our research focuses on identifying cellular and molecular mechanisms of immunosuppression and immunotoxin-mediated antitumor response in animal models of brain tumors. We aim to support our ongoing clinical trials and improve brain tumor patient outcomes through preclinical therapy studies. Our research is funded by federal and foundation grants. 

We seek a highly motivated candidate for a laboratory research analyst (LRA1) position to perform cell culture, molecular biology, immunohistochemistry, and animal research using brain tumor models. This candidate will work alongside a talented team of researchers under the supervision of the Principal Investigator in the Department of Neurosurgery. 

Primary Responsibilities 

· Perform essential cell culture work on human and mouse cells for in vitro and in vivo studies. 

· Design and perform molecular assays, including but not limited to DNA/RNA isolation for next-generation sequencing testing by external vendors, PCR, qPCR, SDS-PAGE gels, western blot, and ELISA. 

· Perform experiments in mice, including breeding, intracranial surgeries, intraperitoneal/subcutaneous injections, weighing, post-surgical monitoring of animals, and preparation of tissues for flow cytometry, histology, RNA/DNA/protein isolation. 

· Operate laboratory equipment required for specific tests. 

· Prepare and maintain reagents, buffers, and media for experiments. 

· Maintain records and documentation of sample acquisitions and all work performed in an organized lab notebook and a shared institutional database. 

· Prepare and execute work independently, with minimal input from the supervisor or principal investigator. 

· Review journals, abstracts, and scientific literature to obtain information to aid in the design and development of procedures and techniques. 

· Generate graphs, slides, and protocols for presentations and publications. 

· Communicate results to the PI and other lab members in team meetings. 

· The position will involve supervising technicians and students. 

· Perform other related duties as required by the supervisor. 

Job Qualifications 

· Bachelor's or Master’s degree in biological sciences or other directly related scientific fields. 

· Work requires a minimum of 3-5 years of laboratory research experience. 

· A background in cancer biology is a plus. 

· Experience using preclinical mouse models of disease is a plus. 

· Ability to handle and troubleshoot tasks and prioritize research projects effectively. 

· Ability to work independently and as a part of a collaborative research team. 

· Must be detail-oriented, well organized, and approach laboratory procedures with critical thinking of the technical aspects. 

· Authorized to work in the US. 

Anticipated Pay Range:

Duke University offers an annual base salary range for this position of USD $50,439.00 to USD $76,417.00. When extending an offer, Duke University considers factors such as (but not limited to) the scope and responsibilities of the position, the candidate's work experience, education/training, key skills, internal peer equity, as well as market and organizational considerations.

Your total compensation extends beyond your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more at: https://hr.duke.edu/benefits/

Education

Work requires a bachelor's degree in botany, biology, zoology,psychology or other directly related scientific field.

Experience

Work requires two years of research experience. A related master'sdegree may offset required ye ars of experience on a 1:1 basis, e.g., atwo year master'sdegree in lie u of two years of experience.OR AN EQUIVALENT COMBINATION OF RELEVANT ED UCATION AND/OR EXPERIENCE

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.