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LAB RESEARCH ANALYST I - Human Vaccine Institute

Req ID:  2341
Date:  Aug 4, 2019

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER

School of Medicine:


Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.


Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.


Laboratory Research Analyst I
We are seeking a detail-oriented scientist to fulfill a key role as Research Analyst 1 to perform multiplexed binding antibody assays for high profile vaccine clinical trials for HIV, malaria, and other infectious diseases in an immune monitoring core lab. The study results generated by the person in this role will inform human clinical and pre-clinical trials for vaccine development and efficacy. The person in this role will also play a key role in assay development and validation and in testing feasibility of novel methods.  This person must be very organized, possess excellent communication skills, have a high level of technical precision, be interested in assay development and optimization, enjoy working in a fast-paced lab environment with multiple priorities, and be able to work well as part of a team. Job functions include:

  • Perform complex and highly technical assays in the laboratory to evaluate binding antibody responses in samples from clinical and preclinical HIV and infectious disease vaccine trials.  Carefully and accurately document assay conditions, results, and quality control findings and report them promptly to meet deadlines. 
  • Play a key role in the development and validation of new assays, participating in discussions of next steps for follow up assays and in assay design.
  • Perform multiplex immunoassays and other assays in the lab to develop new methods and protocols, optimize reagents, test various conditions, and determine feasibility of assays using novel antigens. 
  • Assist with data analysis and writing of qualification and validation documents, SOPs, and data manuscripts as directed by the PI and supervisor.
  • Assist the laboratory and project managers by contributing to the overall effort to streamline the workload, improve the efficiency of the immune-monitoring core, and contribute to the daily laboratory effort to adhere to Good Clinical Laboratory Practice (GCLP) guidelines.
  • Maintain laboratory and associated equipment in a clean, well-ordered, and functional manner.  Keep supplies on hand with a well-planned inventory and ordering system.   
  • Maintain laboratory notebook in an orderly fashion for tracking experiments and results. Provide written updates of work each week.


Education, Skills, & Experience Preferences

  • Bachelor’s degree in biological science or related field
  • Strong background in laboratory techniques with technical precision
  • Two years of research experience or equivalent combination of relevant education and research experience
  • Must be able to manage multiple and rapidly changing priorities and have the ability to quickly learn new skills
  • Must be detail-oriented and well organized with strong communication skills and the ability to work in a fast-paced interactive team environment.
  • Solid mathematical skills, especially with regard to the calculation of weights, volumes and solution concentrations
  • Computer literate, especially with regard to Microsoft Excel, database systems and graphing software



Minimum Qualifications


Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.


Work requires two years of research experience. A related master's degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE


Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh

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