Work Arrangement: 
Requisition Number:  246078
Regular or Temporary:  Regular

Durham, NC, US, 27710

Personnel Area:  MEDICAL CENTER
Date:  May 30, 2024

This Position is Fully Fully Grant Funded

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.


Duke Human Vaccine Institute



The Duke Human Vaccine Institute (DHVI) is a multi-disciplinary research organization in the School of Medicine focused on basic, translational and clinical research to develop novel vaccines, therapeutics and diagnostics for infectious diseases that impact global health.   


A shared resource within the DHVI is the Duke Regional Biocontainment Laboratory (RBL). The RBL is a biosafety level-3 (BSL3) facility that provides safe and secure high-containment laboratory space to support infectious disease research. The DHVI is recruiting a BSL3 Training Mentor to provide on-site safety training and mentoring of workers assigned to the RBL for research in high-containment.  While the primary responsibility of the position will be to provide training for BSL3 workers, the individual will also be trained in, and expected to provide, scientific assay support to the core service units within the RBL. 




Training Duties 

  • Develop and deliver biosafety training programs to workers assigned to BSL3, with an emphasis on hands-on learning activities; includes orientation training and routine refreshers
  • Serve as a mentor for workers assigned to BSL3 
  • Evaluate and improve safety training programs 
  • Serve as a training instructor for the Duke Infectious Disease Response Training (DIDRT) program 
  • Participate as a member of the Duke Select Agent Team and assist in the delivery of training of personnel who conduct Select Agent research to assure compliance with the Select Agent Final Rule, and with all written Select Agent Plans (Incident Response, Safety, and Security). Participate in Select Agent drills and tabletop exercises. 
  • Work to improve/optimize existing safety SOPs 


Scientific Duties 

  • Propagate bacteria and virus at BSL2 and BSL3
  • Train and become proficient at in vitro end-point assays (Luminex, ELISA, Microneutralization, Plaque) as needed 
  • Maintain electronic documentation of research activities in real time according to standardized recordkeeping procedures 
  • Manage and complete all assigned research tasks/projects in accordance with standardized operating procedures and in full compliance with all safety protocols. 
  • Perform other duties as requested by direct supervisor (DHVI Safety Manager 


The successful applicant must be eligible for and willing to: 

  • Work with hazardous biological agents handled at BSL2 and BSL3 
  • Work with small animals handled at ABSL2 and ABSL3 
  • Comply with vaccination requirements when necessary 
  • Complete US Department of Justice screening for Select Agent registration 
  • Complete Select Agent registration at Tier 1 
  • Achieve external certification for independent work at BSL3 


  • Education/Training: Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.
  • Experience: Work requires five years of research experience. A related master's degree may offset required years of experience on a 1:1 basis, e.g., a two-year master's degree in lieu of two years of experience. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE.


  • Master’s degree in Biology, Microbiology, Virology, or related scientific field. Ph. D degree preferred.
  • Previous experience teaching others to work safety in BSL3.
  • Ability to communicate clearly in oral and written form.
  • Ability to work with information systems, automated, and technical equipment.
  • Strong background in biosafety while working in a research environment.
  • Proficient in technical writing and safety training.
  • Previous laboratory experience in at least one of the following fields: bacteriology, virology, immunology, and/or molecular biology.
  • Excellent interpersonal skills and experience working with researchers with diverse backgrounds and experiences.



Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh